Removing unnecessary obstacles to randomised trials
نویسندگان
چکیده
منابع مشابه
Removing unnecessary obstacles to randomised trials
Since their introduction in the middle of the 20 Century, randomised trials of sufficiently large size have provided reliable assessments of the safety and efficacy of treatments that have produced substantial improvements in health. During the past decade, however, increasingly onerous (albeit well-meaning) regulation and related bureaucracy have made clinical trials much more difficult and co...
متن کاملIntroducing “Agreement on what to Measure in Randomised Controlled Trials in Burn Care” Research Project
پروژه پژوهشی "توافق درباره‌ی پیامدهای قابل اندازه‌گیری در کارآزمایی های کنترل‌دار مربوط به مراقبت‌های سوختگی" توسط گروهی از پژوهش‌گران با تجربه، در حوزه سوختگی، زیر نظر دکتر Young از کشور انگلستان در حال انجام می‌باشد. هدف نهایی از انجام این مطالعه، تهیه و تدوین مجموعه‌ای از پیامدهای اساسی (core outcome set (COS)) است که در گزارش کارآزمایی های شاهد‌دار تصادفی مربوط به مراقبت‌های سوختگی باید مور...
متن کاملRemoving the cervix at hysterectomy: an unnecessary intervention?
OBJECTIVE : To evaluate the long-term outcomes in women who underwent total abdominal hysterectomy (TAH) and subtotal abdominal hysterectomy (sub-TAH). METHODS : Two hundred seventy-nine women between 7 and 11 years (mean 9 years) of follow-up who participated in a previously published randomized, double-blind, multicenter trial comparing TAH and sub-TAH were invited to complete questionnaire...
متن کاملRemoving Unnecessary Variables from Horn Clause Verification Conditions
Verification conditions (VCs) are logical formulas whose satisfiability guarantees program correctness. We consider VCs in the form of constrained Horn clauses (CHC) which are automatically generated from the encoding of (an interpreter of) the operational semantics of the programming language. VCs are derived through program specialization based on the unfold/fold transformation rules and, as ...
متن کاملClear obstacles and hidden challenges: understanding recruiter perspectives in six pragmatic randomised controlled trials
BACKGROUND Recruitment of sufficient participants in an efficient manner is still widely acknowledged to be a major challenge to the mounting and completion of randomised controlled trials (RCTs). Few recruitment interventions have involved staff undertaking recruitment. This study aimed i) to understand the recruitment process from the perspective of recruiters actively recruiting RCT particip...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Trials
سال: 2013
ISSN: 1745-6215
DOI: 10.1186/1745-6215-14-s1-i2